This post was updated on June 17th, 2022
By Kym Campbell, BSc. | Updated June 17th, 2022
If you’re confused about gluten and polycystic ovarian syndrome, then you’re in good company.
Some people say going gluten-free is good for PCOS. But others say it’s unnecessary at best, and possibly harmful.
What’s the truth?
In my free 30-Day PCOS Diet Challenge I make it pretty clear where I stand on this question. Sure, there’s no direct evidence linking PCOS and gluten. But what we do have, is a lot of indirect information that can inform our decision-making.
In this article I’m going to show you why going gluten-free is a powerful PCOS natural treatment. I’ll also provide information on how to do it successfully.
If you’re ready to cut out gluten already, then you can also download this 3-Day PCOS meal plan.
1. Wheat Allergy, Celiac Disease, & Gluten Sensitivity
Celiac disease is an autoimmune disorder where gluten damages the small intestine. It affects around 1 in 100 people worldwide . Wheat allergy is a gluten-related allergic disorder that affects only 1 in 1000 people . Because wheat allergy and celiac disease are so rare, many experts will claim that for most people, going gluten-free is unnecessary.
Non-celiac gluten sensitivity (NCGS) is a different story though. Also known as gluten sensitivity or gluten intolerance, NCGS may affect as much as 15% of the population . People with gluten sensitivity have a similar problem with gluten as celiac sufferers. The difference though is that they don’t have antibodies that cause intestinal damage .
Because of this, gluten sensitivity is hard to diagnose. An intestinal biopsy isn’t helpful and there are no reliable blood tests . It’s also largely glossed over by those that argue that a gluten-free diet can be harmful.
2. The Link Between PCOS & Gluten Sensitivity
In my experience, most women with PCOS have some form of gluten intolerance. This is true whether they’re aware of it or not. This view is informed both by the scientific literature and real-world experience.
The predisposing factors for non-celiac gluten sensitivity are:
- Autoimmune disorders [6, 7]
- Functional gastrointestinal disorders [8-11]
- Being female [12-14]
- Neurological disorders [15-17]
- Eating disorders 
- First-degree relatives with celiac disease [12, 17]
- Food allergies and intolerance [17-19]
Through my Beat PCOS 10-Week Program, I’ve had the honor of working with thousands of women with PCOS. Very few of them have not met at least two of these criteria. While still controversial, there’s growing evidence that PCOS is an autoimmune disorder [20, 21].
Autoimmune thyroid disease is also a common comorbidity of PCOS. It affects between 18-40% of women with PCOS. This is approximately three times the rate observed in women without PCOS . A large percentage of these women have what’s known as subclinical hypothyroidism . This means that a diagnosis is easy to miss unless your doctor knows what to look for.
For anyone with PCOS, with any kind of thyroid dysfunction, going gluten-free is especially helpful [24-26].
3. How To Diagnose Gluten Sensitivity
Non-celiac gluten sensitivity can be hard to diagnose. This is because there aren’t any sensitive and specific diagnostics biomarkers .
There are many labs and testing companies that offer gluten sensitivity testing. But despite best efforts, these are unreliable.
Celiac disease and wheat allergy must first be excluded. An exclusion diet with a challenge test is then needed. For a formal diagnosis, the challenge test must be double-blinded and placebo-controlled. The Salerno experts’ criteria describe this process . Despite its scientific rigor, there are many practical limitations to this approach .
The challenges in diagnosing gluten sensitivity make it hard to prove that gluten is bad for women with PCOS. But from a practical perspective, we can make things much simpler.
As explained above, we know that women with PCOS are at high risk of having some kind of gluten intolerance. But rather than investing in unreliable tests or complicated clinical protocols, we can find the right answer easily.
Go strictly gluten-free for at least a month and see for yourself. You can then do your own challenge test by loading up on gluten-rich foods again. If you have subclinical gluten intolerance, it’s likely to reveal itself to you.
4. The Health Benefits Of Going Gluten-Free
As a key aspect of a PCOS diet, going gluten-free can contribute to the following health outcomes:
- Weight loss
- Improved ovulation
- Better gut health
- Improved health skin
- Elimination of brain fog
- Better sleep quality
- Improved emotional regulation
These are big claims, right? Linking a single diet change to a specific health outcome is scientifically challenging. It requires a combination of mechanistic data, epidemiological studies, and randomized controlled trials.
The truth is, we don’t have this kind of data.
What we do have though is a lot of real-life case studies. That isn’t enough to pass rigorous scientific scrutiny but it’s more than enough to see that it works.
Going gluten-free is a consistent theme in many of my PCOS success stories. Here are a few quotes from my Beat PCOS 10-Week program participants.
“…gluten, in particular, was definitely my worst enemy.” Karina K. Lost 60 lbs and achieved her goal weight.
“What’s changed? I have cut all gluten, dairy, soy, and sugars out of my diet.” Raynetta. Lost 50 lbs and fixed her hirsutism.
“The first thing I noticed when I started eating healthy was that my stomach was no longer swollen after I ate.” Hanna. Fixed her period and fell pregnant naturally.
“I cut out all processed/packaged foods and meats, all gluten, all dairy (except butter), soy, and all high GI carbs.” LeeAnne Soule. Lost 65 lbs and fixed EVERYTHING.
5. How To Go Gluten-Free The Right Way
If you’re ready to go gluten-free to help keep your PCOS in check, then you need to know that there’s a “right way” and a “wrong way” to go about it.
Gluten is a group of proteins found in wheat, rye, and barley. Bread, pasta, pizza, and breakfast cereals are obvious foods to avoid with PCOS. But it’s also found in many processed foods like sauces, dressings, and snacks.
One of the biggest criticisms of a gluten-free diet is that it’s not healthy. Experts have shown that gluten-free processed grain products are often lower in iron, zinc, and potassium . As a result, a gluten-free diet may increase the risk for nutritional deficiencies .
These studies show us that switching out normal foods for gluten-free analogs is not likely to help your cause. What you need instead is a whole-food-based diet that happens to exclude gluten.
A healthy PCOS diet is mostly comprised of healthy fats, protein, and non-starchy vegetables. Starchy vegetables (like sweet potatoes) and gluten-free whole grains need to be consumed in moderation. In combination, these steps reduce inflammation. They also ensure better insulin regulation. Along with hyperandrogenism, inflammation and insulin resistance are the primary drivers of PCOS [31-34]. By addressing these issues, most symptoms can be managed more effectively.
For more information, click here for a list of foods to eat and foods to avoid with PCOS. You can also download this PCOS Diet Cheat Sheet and Foods to Avoid Checklist.
Many women find this free 3-Day Meal Plan is a helpful starting place for going gluten-free with PCOS.
The Bottom Line
Experts are right to say that there’s no direct link between PCOS and gluten. That’s technically true, but it’s missing the point. Most women with PCOS have some kind of gluten intolerance whether they realize it or not.
It makes sense for every woman with PCOS to try a gluten-free diet for at least a month. There are no meaningful risks in doing so, yet the benefits can be life-changing. Rather than spend time and money on diagnostic testing, it’s best to try it and see for yourself. After all, your real-life results are the only thing that matters.
Ready To Take The Next Step?
What are the signs and symptoms of gluten sensitivity? Common symptoms of gluten sensitivity include abdominal pain, eczema and/or rash, migraine headaches, “brain fog”, chronic fatigue, diarrhea, depression, anemia, tingling of fingertips, and joint pain.
What are some PCOS-friendly gluten-free grains? Suitable gluten-free grains include quinoa, amaranth, buckwheat, rice, corn, and oats. It’s important when eating these foods to do so in a way that doesn’t cause high blood glucose levels. This is further explained here.
How does gluten affect my PCOS? Gluten increases the permeability of the intestinal lining. This is what’s referred to as “leaky gut” syndrome. Increased gut permeability causes an inflammatory response. Chronic inflammation is one of the underlying causes of PCOS. Through this pathway, gluten consumption can make PCOS symptoms worse.
What do I do if a gluten-free diet doesn’t help? Gluten isn’t the only food that causes symptoms associated with gluten sensitivity. Dairy products can cause similar problems in some people. This is why I recommend a gluten and dairy-free diet for PCOS. The next step, beyond gluten and dairy, is to try a low FODMAP diet.
Since 2010, Kym Campbell has used evidence-based diet and lifestyle interventions to manage her PCOS. After getting her symptoms under control and falling pregnant naturally, Kym now advocates for dietary change as part of any PCOS treatment plan. Combining rigorous science and clinical advice with a pragmatic approach to habit change, Kym is on a mission to show other women how to take back control of their health and fertility. Read more about Kym and her team here.
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